Delamanid requires monitoring of which parameter?

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Multiple Choice

Delamanid requires monitoring of which parameter?

Explanation:
Delamanid can slow the heart’s electrical repolarization, which shows up as prolongation of the QT interval on an ECG. That’s why the key thing to monitor is the QT interval. Before starting therapy, get a baseline ECG, and then check it again during treatment at appropriate intervals. Keeping electrolytes in check and avoiding other drugs that also lengthen the QT can reduce risk. If the QT interval becomes significantly prolonged (for example, a QTc around or above 500 ms, or a large rise from baseline), consider adjusting or stopping delamanid.

Delamanid can slow the heart’s electrical repolarization, which shows up as prolongation of the QT interval on an ECG. That’s why the key thing to monitor is the QT interval. Before starting therapy, get a baseline ECG, and then check it again during treatment at appropriate intervals. Keeping electrolytes in check and avoiding other drugs that also lengthen the QT can reduce risk. If the QT interval becomes significantly prolonged (for example, a QTc around or above 500 ms, or a large rise from baseline), consider adjusting or stopping delamanid.

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