In the 3HP latent TB regimen, which drug is used weekly with isoniazid?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Prepare for the Antitubercular Drugs Test with our extensive questions, flashcards, and explanations. Master your understanding before your exam.

Multiple Choice

In the 3HP latent TB regimen, which drug is used weekly with isoniazid?

Explanation:
In the 3HP approach for latent TB infection, you complete therapy in three months by taking isoniazid with a rifamycin once a week. The reason rifapentine fits this weekly schedule is its longer half-life, which allows a single weekly dose to maintain sufficient drug exposure when paired with isoniazid. This makes the regimen effective while improving adherence compared to daily therapy. The other drugs listed don’t fit this latent-TB weekly strategy: pyrazinamide and ethambutol are used in active TB regimens (or in different phases), whereas rifapentine’s pharmacokinetics specifically enable the convenient once-weekly combination with isoniazid.

In the 3HP approach for latent TB infection, you complete therapy in three months by taking isoniazid with a rifamycin once a week. The reason rifapentine fits this weekly schedule is its longer half-life, which allows a single weekly dose to maintain sufficient drug exposure when paired with isoniazid. This makes the regimen effective while improving adherence compared to daily therapy. The other drugs listed don’t fit this latent-TB weekly strategy: pyrazinamide and ethambutol are used in active TB regimens (or in different phases), whereas rifapentine’s pharmacokinetics specifically enable the convenient once-weekly combination with isoniazid.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy