Pyrazinamide is associated with which adverse effect?

Prepare for the Antitubercular Drugs Test with our extensive questions, flashcards, and explanations. Master your understanding before your exam.

Multiple Choice

Pyrazinamide is associated with which adverse effect?

Explanation:
Pyrazinamide is known for causing hyperuricemia, which can lead to gout, and it can also cause hepatotoxicity. This adverse effect profile is distinctive for Pyrazinamide compared with the others: isoniazid more commonly causes neuropathy and liver toxicity, rifampin can cause hepatotoxicity and urine/tears/orange discoloration, and ethambutol can lead to optic neuritis. So the adverse effect most characteristically associated with this drug is elevated uric acid (hyperuricemia/gout), with hepatotoxic risk as an additional concern.

Pyrazinamide is known for causing hyperuricemia, which can lead to gout, and it can also cause hepatotoxicity. This adverse effect profile is distinctive for Pyrazinamide compared with the others: isoniazid more commonly causes neuropathy and liver toxicity, rifampin can cause hepatotoxicity and urine/tears/orange discoloration, and ethambutol can lead to optic neuritis. So the adverse effect most characteristically associated with this drug is elevated uric acid (hyperuricemia/gout), with hepatotoxic risk as an additional concern.

Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy