What is the role of clofazimine in TB treatment and a notable side effect?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Prepare for the Antitubercular Drugs Test with our extensive questions, flashcards, and explanations. Master your understanding before your exam.

Multiple Choice

What is the role of clofazimine in TB treatment and a notable side effect?

Explanation:
Clofazimine is a second-line anti-TB drug used mainly in regimens for multidrug-resistant TB, rather than for drug-susceptible TB or latent TB. Its standout side effect is skin discoloration, producing a reddish-brown to black tint that can persist for months and may darken with sun exposure. This cosmetic change is a well-known and defining feature of the drug, which is why it’s emphasized in exams. While some other adverse effects can occur (digestive upset, potential effects on liver function, and rare cardiac effects), the most distinctive and frequently tested pairing is its use in MDR-TB regimens with the accompanying skin discoloration.

Clofazimine is a second-line anti-TB drug used mainly in regimens for multidrug-resistant TB, rather than for drug-susceptible TB or latent TB. Its standout side effect is skin discoloration, producing a reddish-brown to black tint that can persist for months and may darken with sun exposure. This cosmetic change is a well-known and defining feature of the drug, which is why it’s emphasized in exams. While some other adverse effects can occur (digestive upset, potential effects on liver function, and rare cardiac effects), the most distinctive and frequently tested pairing is its use in MDR-TB regimens with the accompanying skin discoloration.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy