What is XDR-TB and its definition?

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Multiple Choice

What is XDR-TB and its definition?

Explanation:
XDR-TB is a form of extensively drug-resistant tuberculosis. It means the TB strain is MDR, which already means resistance to isoniazid and rifampin, and it also has additional resistance to at least one fluoroquinolone and at least one of the second-line injectable drugs (such as amikacin, kanamycin, or capreomycin). This combination severely limits effective treatment options and is associated with worse outcomes. The other scenarios described—resistance only to isoniazid, resistance to all first-line drugs, or MDR-TB with no resistance to second-line drugs—do not meet the defining pattern of XDR-TB.

XDR-TB is a form of extensively drug-resistant tuberculosis. It means the TB strain is MDR, which already means resistance to isoniazid and rifampin, and it also has additional resistance to at least one fluoroquinolone and at least one of the second-line injectable drugs (such as amikacin, kanamycin, or capreomycin). This combination severely limits effective treatment options and is associated with worse outcomes. The other scenarios described—resistance only to isoniazid, resistance to all first-line drugs, or MDR-TB with no resistance to second-line drugs—do not meet the defining pattern of XDR-TB.

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