Which drug should be avoided in pregnancy due to risk to the fetus?

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Multiple Choice

Which drug should be avoided in pregnancy due to risk to the fetus?

Explanation:
Streptomycin should be avoided in pregnancy because it is an aminoglycoside with known teratogenic effects, especially fetal ototoxicity that can cause irreversible hearing loss in the newborn. These drugs cross the placenta and can damage the developing inner ear, making them contraindicated during pregnancy. In contrast, isoniazid, rifampin, and ethambutol are generally considered safer options for use in pregnant patients when monitored appropriately, with attention to issues like neuropathy from isoniazid (prevented with pyridoxine) and optic neuritis from ethambutol.

Streptomycin should be avoided in pregnancy because it is an aminoglycoside with known teratogenic effects, especially fetal ototoxicity that can cause irreversible hearing loss in the newborn. These drugs cross the placenta and can damage the developing inner ear, making them contraindicated during pregnancy. In contrast, isoniazid, rifampin, and ethambutol are generally considered safer options for use in pregnant patients when monitored appropriately, with attention to issues like neuropathy from isoniazid (prevented with pyridoxine) and optic neuritis from ethambutol.

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