Which of the following is true regarding bedaquiline monitoring?

• A. Requires ECG QT monitoring and liver function tests
• B. No monitoring is necessary
• C. Only visual testing is required
• D. Only renal function is monitored

Answer: (B)

Bedaquiline has safety signals you must actively watch for: it can prolong the QT interval on the ECG and can cause liver injury. Because of the risk of dangerous arrhythmias, an ECG should be done at baseline and then periodically during treatment to monitor QTc. Liver function tests are also important, with baseline values and repeats during therapy to catch potential hepatotoxicity early. Visual testing won’t reveal cardiac repolarization changes or liver injury, and focusing only on renal function misses the main risks. So, monitoring these two areas—ECG QTc and liver function tests—is essential, rather than assuming no monitoring is needed.